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Normal Pancreas
As you study this slide, note that scattered amongst the pink staining
glandular cells are scattered foci of lighter staining cells. The cells
staining dark pink are the cells of the exocrine pancreas, which produce
digestive enzymes. The scattered lighter foci are called the Islets of
Langerhans and they form the endocrine pancreas which makes 2 hormones
involved in maintaining blood glucose levels.
Normal pancreas (100X2.0)
Light patches are islets of Langerhans. Darker
regions are enzyme-producing cells.
Diabetic Pancreas
In this slide, there appear to be fewer glandular cells and more connective
tissue throughout the pancreas. It is very difficult to find a recognizable
Islet of Langerhans. See if you can find one.
Diabetic pancreas (100X2.0)
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Copyright 2020: Augustine G. DiGiovanna, Ph.D., Salisbury University, Maryland
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