Normal lung (40X2.0) Normal lung (100X2.0)
Much normal tissue creates large surface area Much normal tissue creates large surface area
with many capillaries, many small air spaces. Large with many capillaries, which are filled with
vessel at extreme left, large airway at lower right RBCs (red cells)
Ghon tubercle - entire (40X1.0) Ghon tubercle (40X2.0)
Tubercle in center with necrotic core surrounded by Normal lung (lower left), capsule (granular and fibrous
capsule, normal lung on extreme left and right layers), and core of necrotic material (center to right edge)
Ghon tubercle (100X1.6) Ghon tubercle (400X2.0)
Macrophages (left), fibrous capsule (center), necrotic Macrophages (round dark blue at left), fibrous capsule
region (right) (right)
Ghon tubercle (400X2.8) Ghon tubercle (400X2.8)
Macrophages (round dark blue at left), fibrous capsule Central amorphous acellular necrotic region
(right)
Compare the dense arrangement of material in the granuloma with the open, air-filled normal lung tissue surrounding it.
